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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 1
1975 1
1976 1
1984 1
1985 2
1987 1
1988 1
1990 1
1992 1
1993 2
1994 2
1995 3
1996 1
1997 3
1998 2
1999 3
2000 1
2001 4
2002 6
2003 4
2004 2
2005 2
2006 2
2007 9
2008 7
2009 9
2010 7
2011 12
2012 11
2013 5
2014 11
2015 8
2016 15
2017 9
2018 13
2019 20
2020 17
2021 25
2022 14
2023 15
2024 3

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227 results

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Page 1
Next-Generation Sequencing Strategies.
Levy SE, Boone BE. Levy SE, et al. Cold Spring Harb Perspect Med. 2019 Jul 1;9(7):a025791. doi: 10.1101/cshperspect.a025791. Cold Spring Harb Perspect Med. 2019. PMID: 30323017 Free PMC article. Review.
More than a decade ago, the term "next-generation" sequencing was coined to describe what was, at the time, revolutionary new methods to sequence RNA and DNA at a faster pace and cheaper cost than could be performed by standard bench-top protocols. Since then, the field of …
More than a decade ago, the term "next-generation" sequencing was coined to describe what was, at the time, revolutionary new methods to seq …
Immunotherapy efficacy on mismatch repair-deficient colorectal cancer: From bench to bedside.
Lizardo DY, Kuang C, Hao S, Yu J, Huang Y, Zhang L. Lizardo DY, et al. Biochim Biophys Acta Rev Cancer. 2020 Dec;1874(2):188447. doi: 10.1016/j.bbcan.2020.188447. Epub 2020 Oct 6. Biochim Biophys Acta Rev Cancer. 2020. PMID: 33035640 Free PMC article. Review.
Furthermore, we address the potential strategies to sensitize pMMR/MSS CRC to immunotherapy by converting an immunologically "cold" microenvironment into a "hot" one....
Furthermore, we address the potential strategies to sensitize pMMR/MSS CRC to immunotherapy by converting an immunologically "cold" m …
Cold water immersion attenuates anabolic signaling and skeletal muscle fiber hypertrophy, but not strength gain, following whole-body resistance training.
Fyfe JJ, Broatch JR, Trewin AJ, Hanson ED, Argus CK, Garnham AP, Halson SL, Polman RC, Bishop DJ, Petersen AC. Fyfe JJ, et al. J Appl Physiol (1985). 2019 Nov 1;127(5):1403-1418. doi: 10.1152/japplphysiol.00127.2019. Epub 2019 Sep 12. J Appl Physiol (1985). 2019. PMID: 31513450 Free article.
We determined the effects of cold water immersion (CWI) on long-term adaptations and post-exercise molecular responses in skeletal muscle before and after resistance training. ...Training-induced increases in heat shock protein (HSP) 27 protein content were attenuated for …
We determined the effects of cold water immersion (CWI) on long-term adaptations and post-exercise molecular responses in skeletal mu …
Cold Ablation Robot-Guided Laser Osteotome (CARLO()): From Bench to Bedside.
Ureel M, Augello M, Holzinger D, Wilken T, Berg BI, Zeilhofer HF, Millesi G, Juergens P, Mueller AA. Ureel M, et al. J Clin Med. 2021 Jan 24;10(3):450. doi: 10.3390/jcm10030450. J Clin Med. 2021. PMID: 33498921 Free PMC article.
BACKGROUND: In order to overcome the geometrical and physical limitations of conventional rotating and piezosurgery instruments used to perform bone osteotomies, as well as the difficulties in translating digital planning to the operating room, a stand-alone robot-guided laser sy …
BACKGROUND: In order to overcome the geometrical and physical limitations of conventional rotating and piezosurgery instruments used to perf …
Development of mRNA manufacturing for vaccines and therapeutics: mRNA platform requirements and development of a scalable production process to support early phase clinical trials.
Whitley J, Zwolinski C, Denis C, Maughan M, Hayles L, Clarke D, Snare M, Liao H, Chiou S, Marmura T, Zoeller H, Hudson B, Peart J, Johnson M, Karlsson A, Wang Y, Nagle C, Harris C, Tonkin D, Fraser S, Capiz L, Zeno CL, Meli Y, Martik D, Ozaki DA, Caparoni A, Dickens JE, Weissman D, Saunders KO, Haynes BF, Sempowski GD, Denny TN, Johnson MR. Whitley J, et al. Transl Res. 2022 Apr;242:38-55. doi: 10.1016/j.trsl.2021.11.009. Epub 2021 Dec 4. Transl Res. 2022. PMID: 34871810 Free PMC article. Review.
To date, production processes have either not been disclosed or are bench-scale in nature and cannot be readily adapted to clinical and commercial scale production. ...Finally, we discuss continued challenges in raw material identification, sourcing and supply, and the …
To date, production processes have either not been disclosed or are bench-scale in nature and cannot be readily adapted to clinical a …
Dendritic cell vaccine of gliomas: challenges from bench to bed.
Zheng Y, Ma X, Feng S, Zhu H, Chen X, Yu X, Shu K, Zhang S. Zheng Y, et al. Front Immunol. 2023 Sep 14;14:1259562. doi: 10.3389/fimmu.2023.1259562. eCollection 2023. Front Immunol. 2023. PMID: 37781367 Free PMC article. Review.
As the most malignant subtype of glioma, glioblastoma (GBM) is barely effectively treated by traditional therapies (surgery combined with radiochemotherapy), resulting in poor prognosis. Meanwhile, due to its "cold tumor" phenotype, GBM fails to respond to multiple immunot …
As the most malignant subtype of glioma, glioblastoma (GBM) is barely effectively treated by traditional therapies (surgery combined with ra …
Natalizumab: Perspectives from the Bench to Bedside.
Shirani A, Stüve O. Shirani A, et al. Cold Spring Harb Perspect Med. 2018 Dec 3;8(12):a029066. doi: 10.1101/cshperspect.a029066. Cold Spring Harb Perspect Med. 2018. PMID: 29500304 Free PMC article. Review.
Probably no other disease-modifying drug for multiple sclerosis has a more fascinating story than natalizumab from both the bench to bedside perspective and the postmarketing experience standpoint. ...
Probably no other disease-modifying drug for multiple sclerosis has a more fascinating story than natalizumab from both the bench to …
Rhinovirus - From bench to bedside.
To KKW, Yip CCY, Yuen KY. To KKW, et al. J Formos Med Assoc. 2017 Jul;116(7):496-504. doi: 10.1016/j.jfma.2017.04.009. Epub 2017 May 8. J Formos Med Assoc. 2017. PMID: 28495415 Free article. Review.
Rhinovirus has been neglected in the past because it was generally perceived as a respiratory virus only capable of causing mild common cold. Contemporary epidemiological studies using molecular assays have shown that rhinovirus is frequently detected in adult and p …
Rhinovirus has been neglected in the past because it was generally perceived as a respiratory virus only capable of causing mild common …
Leaving the Bench and Finding Your Foundation.
Spiro JE. Spiro JE. Cold Spring Harb Perspect Biol. 2017 Dec 1;9(12):a032904. doi: 10.1101/cshperspect.a032904. Cold Spring Harb Perspect Biol. 2017. PMID: 29196435 Free PMC article. Review.
Scientists who leave the laboratory bench to work for biomedical foundations mobilize and focus resources on the most promising research behind a foundation's mission. ...Many at foundations feel that they have the potential to have an even greater impact than if they had …
Scientists who leave the laboratory bench to work for biomedical foundations mobilize and focus resources on the most promising resea …
From Bench to Bedside-Delivering Gene Therapy for Leber Hereditary Optic Neuropathy.
Chen BS, Yu-Wai-Man P. Chen BS, et al. Cold Spring Harb Perspect Med. 2022 Jul 21;12(6):a041282. doi: 10.1101/cshperspect.a041282. Cold Spring Harb Perspect Med. 2022. PMID: 35863905 Review.
Since the mitochondrial genetic basis for LHON was uncovered in 1988, considerable progress has been made in understanding the pathogenetic mechanisms driving RGC loss, which has enabled the development of therapeutic approaches aimed at mitigating the underlying mitochondrial dy …
Since the mitochondrial genetic basis for LHON was uncovered in 1988, considerable progress has been made in understanding the pathogenetic …
227 results